It took a long six months after a terrible rage virus has wiped out almost the entire population of London. People still managed to defeat the disease, although it was more likely just to destroy its carriers, and they began to create special, well-protected zones where people can live again. However, scientists are against such a development of events, they believe that the virus may return at any time and the epidemic will break out with a new force. Brother and sister return to where they were called for half a year to go through real hell. Long sitting in a protected area quickly bothers them and they go to look for their mother, which eventually turns into a new, even more large-scale disaster.